*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RC9050700
CHEMICAL NAME           : A-Nor-17-alpha-pregn-20-yne-2-beta,17-diol,
                          2-ethynyl-
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H30-O2
MOLECULAR WEIGHT        : 326.52
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * 2-Ethynyl-A-nor-17-alpha-pregn-20-yne-2-beta,17-diol
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 500 ug/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   15TRAW "Preimplantation Stages of Pregnancy, Ciba Foundation Symposium,
   London, 1965," Wolstenholme, G.E.W., and M. O'Connor, eds., Boston, Little,
   Brown and Co., 1965  Volume(issue)/page/year: -,378,1965
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 50 ug/kg
SEX/DURATION            : female 1 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   15TRAW "Preimplantation Stages of Pregnancy, Ciba Foundation Symposium,
   London, 1965," Wolstenholme, G.E.W., and M. O'Connor, eds., Boston, Little,
   Brown and Co., 1965  Volume(issue)/page/year: -,378,1965
 
                            *** END OF RECORD ***