*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RD2530000
CHEMICAL NAME           : C'-Norvincaleukoblastine, 3',4'-didehydro-4'-deoxy-
CAS REGISTRY NUMBER     : 71486-22-1
LAST UPDATED            : 199706
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C45-H54-N4-O8
MOLECULAR WEIGHT        : 779.03
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Navelbine
   * Nor-5'-anhydrovinblastine
   * NVB
   * Vinorelbine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 26 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTKRDX Gan to Kagaku Ryoho.  Cancer and Chemotherapy.  (1-8-9 Yaesu,
   Chuo-ku, Tokyo 103, Japan) V.1-    1974-  Volume(issue)/page/year:
   10,1050,1983
 
                            *** END OF RECORD ***