*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RC8900000
CHEMICAL NAME           : 19-Nor-17-alpha-pregna-4,9-dien-20-yn-3-one,
                          21-chloro-17-hydroxy-
CAS REGISTRY NUMBER     : 3124-93-4
BEILSTEIN REFERENCE NO. : 2011016
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H23-Cl-O2
MOLECULAR WEIGHT        : 330.88
WISWESSER LINE NOTATION : L E5 B666 OV KU MUTJ E1 FQ F1UU1G
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
SYNONYMS/TRADE NAMES :
   * 17-alpha-Chloroethinyl-17-beta-hydroxyestra-4,9-dien-3-one
   * 17-alpha-Chloroethynyl-17-beta-hydroxy-19-nor-4,9-androstadien-3-one
   * 17-alpha-Chloroethynyl-19-nor-4,9-androstadien-17-beta-ol-3-one
   * Ethynerone
   * MK 665
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 1008 mg/kg/4Y-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 3,179,1977
 
                            *** END OF RECORD ***