*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RC0900000
CHEMICAL NAME           : 24-Norchola-20,22-diene-4-carboxaldehyde,
                          2,3-bis(acetyloxy)-14,15:21,23-diepoxy-4,8-
                          dimethyl-11-oxo-1,7,19-trihydroxy-, cyclic
                          4,19-(2-methyl-1-oxobutylacetal), (1-alpha,2-
                          alpha,3-alpha,4-beta(alpha-S),5-alpha,7-alpha,13-alph
                          a,14-beta,15-beta,17- alpha)-
CAS REGISTRY NUMBER     : 87725-70-0
BEILSTEIN REFERENCE NO. : 5698315
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C35-H46-O12
MOLECULAR WEIGHT        : 658.81
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * Meliatoxin A1
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 16 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23,    1978-88. For
   publisher information, see ZYZAEU.  Volume(issue)/page/year: 20,247,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - pig
DOSE/DURATION           : 6400 ug/kg
TOXIC EFFECTS :
   Behavioral - coma
   Cardiac - other changes
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23,    1978-88. For
   publisher information, see ZYZAEU.  Volume(issue)/page/year: 20,247,1985
 
                            *** END OF RECORD ***