*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QS4470250
CHEMICAL NAME           : Nicotinamide,
                          1,4-dihydro-N,1-bis(p-chlorophenyl)-2,6-dimethyl-4-ox
                          o-, monohydrochloride
CAS REGISTRY NUMBER     : 80357-38-6
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H16-Cl2-N2-O2.Cl-H
MOLECULAR WEIGHT        : 423.74
WISWESSER LINE NOTATION : T6N DVJ AR DG& B1 CVMR DG& F1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,4-Dihydro-N,1-bis(p-chlorophenyl)-2,6-dimethyl-4-oxonicotinamide  
   monohydrochloride
   *   1,4-Dihydro-2,6-dimethyl-N,1-bis(p-chlorophenyl)-4-oxo-3-pyridinecarboxa
     mide hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 25,131,1982
 
                            *** END OF RECORD ***