*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RB5875800
CHEMICAL NAME           : A-Nor-5-alpha-androstane-2-alpha,17-beta-diol,
                          2-ethynyl-
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H30-O2
MOLECULAR WEIGHT        : 302.50
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * 2-Ethynyl-A-nor-5-alpha-androstane-2-alpha,17-beta-diol
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1500 ug/kg
SEX/DURATION            : female 1-3 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press,
   1965  Volume(issue)/page/year: -,111,1965
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 2400 ug/kg
SEX/DURATION            : female 1-3 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press,
   1965  Volume(issue)/page/year: -,111,1965
 
                            *** END OF RECORD ***