*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QS4483750
CHEMICAL NAME           : Nicotinamide, N-(2-((p-phenetidino)sulfonyl)ethyl)-,
                          monohydrochloride
LAST UPDATED            : 198311
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H19-N3-O4-S.Cl-H
MOLECULAR WEIGHT        : 385.90
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Nicotinoyltaurinophenetidine hydrochloride
   * N-(2-((p-Phenetidino)sulfonyl)ethyl)nicotinamide hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4650 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 60,249,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 470 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 60,249,1971
 
                            *** END OF RECORD ***