*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QV0100000
CHEMICAL NAME           : Nitric acid, methyl ester
CAS REGISTRY NUMBER     : 598-58-3
BEILSTEIN REFERENCE NO. : 1699872
REFERENCE               : 4-01-00-01254 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C-H3-N-O3
MOLECULAR WEIGHT        : 77.05
WISWESSER LINE NOTATION : WNO1
SYNONYMS/TRADE NAMES :
   * Methylester kyseliny dusicne
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 344 mg/kg
TOXIC EFFECTS :
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   AMRL** Aerospace Medical Research Laboratory Report.  (Aerospace Technical
   Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433)
   Volume(issue)/page/year: TR-77-25,1977
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1275 ppm/4H
TOXIC EFFECTS :
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   AMRL** Aerospace Medical Research Laboratory Report.  (Aerospace Technical
   Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433)
   Volume(issue)/page/year: TR-77-25,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1820 mg/kg
TOXIC EFFECTS :
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   AMRL** Aerospace Medical Research Laboratory Report.  (Aerospace Technical
   Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433)
   Volume(issue)/page/year: TR-77-25,1977
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5942 ppm/4H
TOXIC EFFECTS :
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   AMRL** Aerospace Medical Research Laboratory Report.  (Aerospace Technical
   Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433)
   Volume(issue)/page/year: TR-77-25,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 548 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
   Liver - other changes
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   AMRL** Aerospace Medical Research Laboratory Report.  (Aerospace Technical
   Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433)
   Volume(issue)/page/year: TR-77-25,1977

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***