RTECS NUMBER-QU7400000-Chemical Toxicity Database

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QU7400000
CHEMICAL NAME           : Nitric acid, copper(2+) salt
CAS REGISTRY NUMBER     : 3251-23-8
LAST UPDATED            : 199712
DATA ITEMS CITED        : 42
MOLECULAR FORMULA       : N2-O6.Cu
MOLECULAR WEIGHT        : 187.56
COMPOUND DESCRIPTOR     : Primary Irritant
SYNONYMS/TRADE NAMES :
   * Claycop
   * Copper dinitrate
   * Copper(II) nitrate
   * Copper(2+) nitrate
   * Cupric dinitrate
   * Cupric nitrate
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg
REACTION SEVERITY       : Severe
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   20,563,1982
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg
REACTION SEVERITY       : Severe
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   20,573,1982
 
TYPE OF TEST            : Rinsed with water
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg/4S
REACTION SEVERITY       : Severe
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   20,573,1982
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 794 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   INJPD2 Indian Journal of Pharmacology.  (Dept. of Pharmacology, Baranas
   Hindu Univ., Varanasi 221 005, India)  V.1-    1968(?)-
   Volume(issue)/page/year: 23,153,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   INJPD2 Indian Journal of Pharmacology.  (Dept. of Pharmacology, Baranas
   Hindu Univ., Varanasi 221 005, India)  V.1-    1968(?)-
   Volume(issue)/page/year: 23,153,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 14700 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   INJPD2 Indian Journal of Pharmacology.  (Dept. of Pharmacology, Baranas
   Hindu Univ., Varanasi 221 005, India)  V.1-    1968(?)-
   Volume(issue)/page/year: 23,153,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 430 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   INJPD2 Indian Journal of Pharmacology.  (Dept. of Pharmacology, Baranas
   Hindu Univ., Varanasi 221 005, India)  V.1-    1968(?)-
   Volume(issue)/page/year: 23,153,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17100 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   INJPD2 Indian Journal of Pharmacology.  (Dept. of Pharmacology, Baranas
   Hindu Univ., Varanasi 221 005, India)  V.1-    1968(?)-
   Volume(issue)/page/year: 23,153,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 23300 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   INJPD2 Indian Journal of Pharmacology.  (Dept. of Pharmacology, Baranas
   Hindu Univ., Varanasi 221 005, India)  V.1-    1968(?)-
   Volume(issue)/page/year: 23,153,1991

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   54,7740,1989

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-AUSTRALIA:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-AUSTRALIA:TWA 1 mg(Cu)/m3 (dust) JAN 1993
   
   OEL-BELGIUM:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-BELGIUM:TWA 1 mg(Cu)/m3 (dust) JAN 1993
   
   OEL-DENMARK:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-DENMARK:TWA 1 mg(Cu)/m3 (dust) JAN 1993
   
   OEL-FINLAND:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-FINLAND:TWA 1 mg(Cu)/m3 (dust) JAN 1993
   
   OEL-FRANCE:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-FRANCE:TWA 1 mg(Cu)/m3;STEL 2 mg(Cu)/m3 (dust) JAN 1993
   
   OEL-GERMANY:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-GERMANY:TWA 1 mg(Cu)/m3 (dust) JAN 1993
   
   OEL-HUNGARY:TWA 0.2 mg(Cu)/m3;STEL 0.4 mg(Cu)/m3 (dust) JAN 1993
   
   OEL-INDIA:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-THE NETHERLANDS:TWA 02 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-THE NETHERLANDS:TWA 1 mg(Cu)/m3 (dust) JAN 1993
   
   OEL-THE PHILIPPINES:TWA 1.0 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-POLAND:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-RUSSIA:STEL 0.5 ppm (1 mg(Cu)/m3) (dust) JAN 1993
   
   OEL-SWEDEN:TWA 0.2 mg(Cu)/m3 (resp. dust) JAN 1993
   
   OEL-SWEDEN:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-SWEDEN:TWA 1 mg(Cu)/m3 (total dust) JAN 1993
   
   OEL-SWITZERLAND:TWA 0.1 mg(Cu)/m3;STEL 0.2 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-SWITZERLAND:TWA 1 mg(Cu)/m3;STEL 1 mg(Cu)/m3 JAN 1993
   
   OEL-THAILAND:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-THAILAND:TWA 1 mg(Cu)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993
   
   OEL-UNITED KINGDOM:TWA 1 mg(Cu)/m3 JAN 1993

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 84335
       No. of Facilities: 97 (estimated)
       No. of Industries: 6
       No. of Occupations: 8
       No. of Employees: 738 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 84335
       No. of Facilities: 844 (estimated)
       No. of Industries: 19
       No. of Occupations: 23
       No. of Employees: 13313 (estimated)
       No. of Female Employees: 1746 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***