*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QS4470900
CHEMICAL NAME           : Nicotinamide, N,6-dimethyl-2-(p-toluidino)-
CAS REGISTRY NUMBER     : 78593-71-2
BEILSTEIN REFERENCE NO. : 5061093
LAST UPDATED            : 199803
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H17-N3-O
MOLECULAR WEIGHT        : 255.35
WISWESSER LINE NOTATION : T6NJ BMR D1& CVM1 F1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N,6-Dimethyl-2-(p-toluidino)nicotinamide
   * 3-Pyridinecarboxamide, N,6-dimethyl-2-((4-methylphenyl)amino)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 255 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 15,249,1981
 
                            *** END OF RECORD ***