*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QS4000800
CHEMICAL NAME           : Nicotinamide, 2-amino-N-(p-tolyl)-, hydrochloride
CAS REGISTRY NUMBER     : 51071-58-0
LAST UPDATED            : 199803
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C13-H13-N3-O.Cl-H
MOLECULAR WEIGHT        : 263.75
WISWESSER LINE NOTATION : T6NJ BZ CVMR D1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Amino-N-(p-tolyl)nicotinamide hydrochloride
   * 3-Pyridinecarboxamide, 2-amino-N-(4-methylphenyl)-, hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 116 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 7,695,1973
 
                            *** END OF RECORD ***