*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QR8420000
CHEMICAL NAME           : Nickel(III) oxide
CAS REGISTRY NUMBER     : 1314-06-3
LAST UPDATED            : 199712
DATA ITEMS CITED        : 35
MOLECULAR FORMULA       : Ni2-O3
MOLECULAR WEIGHT        : 165.42
WISWESSER LINE NOTATION : .NI2.O3
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Dinickel trioxide
   * Nickelic oxide
   * Nickel oxide peroxide
   * Nickel peroxide
   * Nickel sesquioxide
   * Nickel trioxide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZVKOA6 Zhurnal Vsesoyuznogo Khimicheskogo Obshchestva im. D.I. Mendeleeva.
   Journal of the D.I. Mendeleeva All-Union Chemical Society.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.5-    1960-
   Volume(issue)/page/year: 19,186,1974
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - mouse Embryo
DOSE/DURATION           : 500 umol/L
REFERENCE :
   PAACA3 Proceedings of the American Association for Cancer Research. (Waverly
   Press, 428 E. Preston St., Baltimore, MD 21202)  V.1-    1954-
   Volume(issue)/page/year: 24,100,1983

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 1 mg(Ni)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   IARC Cancer Review:Animal Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 49,257,1990

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 1 mg(Ni)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,178,1971

   OSHA PEL (Gen Indu):8H TWA 1 mg(Ni)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 1 mg(Ni)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 1 mg(Ni)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 1 mg(Ni)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 0.1 mg(Ni)/m3 JAN 1993
   
   OEL-AUSTRALIA:TWA 1 mg(Ni)/m3 JAN 1993
   
   OEL-BELGIUM:TWA 1 mg(Ni)/m3 (insoluble compounds) JAN 1993
   
   OEL-DENMARK:TWA 0.05 mg(Ni)/m3;Carcinogen JAN 1993
   
   OEL-DENMARK:TWA 1 mg(Ni)/m3 (insoluble compounds) JAN 1993
   
   OEL-FINLAND:TWA 0.1 mg(Ni)/m3;Skin;Carcinogen (insoluble compounds) JAN 1993
   
   OEL-FRANCE:TWA 1 mg(Ni)/m3 JAN 1993
   
   OEL-GERMANY;Carcinogen JAN 1993
   
   OEL-HUNGARY:STEL 0.005 mg(Ni)/m3;Carcinogen (insoluble compounds) JAN 1993
   
   OEL-JAPAN:TWA 1 mg(Ni)/m3;Carcinogen JAN 1993
   
   OEL-THE NETHERLANDS:TWA 0.1 mg(Ni)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 1 mg(Ni)/m3 (insoluble compounds) JAN 1993
   
   OEL-THE PHILIPPINES:TWA 1 mg(Ni)/m3 JAN 1993
   
   OEL-RUSSIA:STEL 0.05 mg(Ni)/m3 JAN 1993
   
   OEL-SWEDEN:TWA 0.1 mg/m3;Carcinogen JAN 1993
   
   OEL-SWEDEN:TWA 0.5 mg(Ni)/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 0.5 mg(Ni)/m3 (insoluble compounds) JAN 1993
   
   OEL-SWITZERLAND:TWA 0.5 mg(Ni)/m3;Carcinogen JAN 1993
   
   OEL-THAILAND:TWA 1 mg(Ni)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.5 mg(Ni)/m3 (insoluble compounds) JAN 1993
   
   OEL-UNITED KINGDOM:TWA 1 mg(Ni)/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO NICKEL, INORGANIC-air:10H CA TWA 0.015 mg(Ni)/m3
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***