*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QR6825000
CHEMICAL NAME           : Nickel(II) fluoride (1:2)
CAS REGISTRY NUMBER     : 10028-18-9
LAST UPDATED            : 199712
DATA ITEMS CITED        : 59
MOLECULAR FORMULA       : F2-Ni
MOLECULAR WEIGHT        : 96.71
WISWESSER LINE NOTATION :  NI  F2
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Nickel difluoride
   * Nickelous fluoride
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 4 mg/kg/24H (Intermittent)
REFERENCE :
   NULSAK Nucleus (Calcutta).  (Dr. A.K. Sharma, Centre of Advanced Studies in
   Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta
   700 019, India)  V.1-    1958-  Volume(issue)/page/year: 29,132,1986
 
TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 4 mg/kg
REFERENCE :
   NULSAK Nucleus (Calcutta).  (Dr. A.K. Sharma, Centre of Advanced Studies in
   Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta
   700 019, India)  V.1-    1958-  Volume(issue)/page/year: 29,132,1986
 
TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 1 mg/kg
REFERENCE :
   NULSAK Nucleus (Calcutta).  (Dr. A.K. Sharma, Centre of Advanced Studies in
   Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta
   700 019, India)  V.1-    1958-  Volume(issue)/page/year: 29,132,1986
 
TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Subcutaneous
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 4 mg/kg
REFERENCE :
   NULSAK Nucleus (Calcutta).  (Dr. A.K. Sharma, Centre of Advanced Studies in
   Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta
   700 019, India)  V.1-    1958-  Volume(issue)/page/year: 29,132,1986
 
TYPE OF TEST            : Sperm Morphology
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 4 mg/kg/4D (Intermittent)
REFERENCE :
   NULSAK Nucleus (Calcutta).  (Dr. A.K. Sharma, Centre of Advanced Studies in
   Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta
   700 019, India)  V.1-    1958-  Volume(issue)/page/year: 29,132,1986

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.1 mg(Ni)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-TWA 2.5 mg(F)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   TOXICOLOGY REVIEW
   ACLSCP Annals of Clinical and Laboratory Science.  (1833 Delancey Pl.,
   Philadelphia, PA 19103) V.1-    1971-  Volume(issue)/page/year: 3,156,1973

   TOXICOLOGY REVIEW
   85DHAX "Medical and Biologic Effects of Environmental Pollutants Series,"
   Washington, DC, National Academy of Sciences, 1972-77
   Volume(issue)/page/year: Ni,168,1975

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 1 mg(Ni)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,178,1971

   OSHA PEL (Gen Indu):8H TWA 1 mg(Ni)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Gen Indu):8H TWA 2.5 mg(F)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 1 mg(Ni)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Construc):8H TWA 2.5 mg(F)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 1 mg(Ni)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Shipyard):8H TWA 2.5 mg(F)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 1 mg(Ni)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

   OSHA PEL (Fed Cont):8H TWA 2.5 mg(F)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 0.1 mg(Ni)/m3 JAN 1993
   
   OEL-AUSTRALIA:TWA 1 mg(Ni)/m3 JAN 1993
   
   OEL-AUSTRALIA:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-BELGIUM:TWA 1 mg(Ni)/m3 (insoluble compounds) JAN 1993
   
   OEL-BELGIUM:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-DENMARK:TWA 0.05 mg(Ni)/m3;Carcinogen JAN 1993
   
   OEL-DENMARK:TWA 1 mg(Ni)/m3 (insoluble compounds) JAN 1993
   
   OEL-DENMARK:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-FINLAND:TWA 0.1 mg(Ni)/m3;Skin;Carcinogen (insoluble compounds) JAN 1993
   
   OEL-FINLAND:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-FRANCE:TWA 1 mg(Ni)/m3 JAN 1993
   
   OEL-FRANCE:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-GERMANY:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-GERMANY;Carcinogen JAN 1993
   
   OEL-HUNGARY:STEL 0.005 mg(Ni)/m3;Carcinogen (insoluble compounds) JAN 1993
   
   OEL-HUNGARY:TWA 1 mg(F)/m3;STEL 2 mg(F)/m3 JAN 1993
   
   OEL-JAPAN:TWA 1 mg(Ni)/m3;Carcinogen JAN 1993
   
   OEL-THE NETHERLANDS:TWA 0.1 mg(Ni)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 1 mg(Ni)/m3 (insoluble compounds) JAN 1993
   
   OEL-THE NETHERLANDS:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 1 mg(Ni)/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-POLAND:TWA 1 mg(F)/m3 JAN 1993
   
   OEL-RUSSIA:STEL 0.05 mg(Ni)/m3 JAN 1993
   
   OEL-SWEDEN:TWA 0.5 mg(Ni)/m3 JAN 1993
   
   OEL-SWEDEN:TWA 2 mg(F)/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 0.5 mg(Ni)/m3 (insoluble compounds) JAN 1993
   
   OEL-SWITZERLAND:TWA 0.5 mg(Ni)/m3;Carcinogen JAN 1993
   
   OEL-SWITZERLAND:TWA 1.8 ppm (1.5 mg(F)/m3);STEL 9.0 ppm JAN 1993
   
   OEL-THAILAND:TWA 1 mg(Ni)/m3 JAN 1993
   
   OEL-THAILAND:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-TURKEY:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.5 mg(Ni)/m3 (insoluble compounds) JAN 1993
   
   OEL-UNITED KINGDOM:TWA 1 mg(Ni)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 2.5 mg(F)/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO NICKEL, INORGANIC-air:10H CA TWA 0.015 mg(Ni)/m3
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 50450
       No. of Facilities: 67 (estimated)
       No. of Industries: 2
       No. of Occupations: 2
       No. of Employees: 85 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 50450
       No. of Facilities: 36 (estimated)
       No. of Industries: 3
       No. of Occupations: 3
       No. of Employees: 36 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***