*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QL3410000
CHEMICAL NAME           : 2-Naphthol, 1-chloro-
CAS REGISTRY NUMBER     : 633-99-8
BEILSTEIN REFERENCE NO. : 1939233
REFERENCE               : 4-06-00-04289 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H7-Cl-O
MOLECULAR WEIGHT        : 178.62
WISWESSER LINE NOTATION : L66J BG CQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-Chloro-2-naphthol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2310 mg/kg
TOXIC EFFECTS :
   Behavioral - withdrawal
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 32(4),55,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 580 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 32(4),55,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 275 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IJPAAO Indian Journal of Pharmacy.  (Bombay, India)  V.1-40(1), 1939-78. For
   publisher information, see IJSIDW.  Volume(issue)/page/year: 30,89,1968
 
                            *** END OF RECORD ***