*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QN2791805
CHEMICAL NAME           : 1,8-Naphthyridine-3-carboxylic acid,
                          1,4-dihydro-7-(3-amino-4-methyl-1-pyrrolidinyl)-1-(1,
                          1- dimethylethyl)-6-fluoro-4-oxo-, trans-(+-)-,
                          monomethanesulfonate, hydrate
CAS REGISTRY NUMBER     : 125197-24-2
LAST UPDATED            : 199103
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H23-F-N4-O3.C-H4-O3-S.H2-O
MOLECULAR WEIGHT        : 476.58
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 33,1344,1990
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 131 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 33,1344,1990
 
                            *** END OF RECORD ***