*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QN2790000
CHEMICAL NAME           : 1,8-Naphthyridine-3-carboxamide, 2-amino-,
                          monohydrochloride, monohydrate
CAS REGISTRY NUMBER     : 42373-29-5
LAST UPDATED            : 198510
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H8-N4-O.Cl-H.H2-O
MOLECULAR WEIGHT        : 242.69
WISWESSER LINE NOTATION : T66 BN JNJ CZ DVZ &GH &QH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 39A69
   * 2-Amino-1,8-naphthyridine-3-carboxamide hydrochloride monohydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 101 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - urine volume increased
   Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
   CNJPAZ Canadian Journal of Pharmaceutical Sciences.  (Toronto, Ont., Canada)
    V.1-16, 1966-81. Discontinued.  Volume(issue)/page/year: 12(1),12,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 22700 ug/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - urine volume increased
   Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
   CNJPAZ Canadian Journal of Pharmaceutical Sciences.  (Toronto, Ont., Canada)
    V.1-16, 1966-81. Discontinued.  Volume(issue)/page/year: 12(1),12,1977
 
                            *** END OF RECORD ***