*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QL5415000
CHEMICAL NAME           : 1-Naphthol, 1,2,3,4-tetrahydro-2-dimethylamino-,
                          benzoate, hydrochloride, dl-(Z)-
CAS REGISTRY NUMBER     : 58782-65-3
LAST UPDATED            : 198803
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C19-H21-N-O2.Cl-H
MOLECULAR WEIGHT        : 331.87
WISWESSER LINE NOTATION : L66&TJ GOVR& HN1&1 &GH -C
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * dl-cis-1-Benzoyloxy-2-dimethylamino-1,2,3,4-tetrahydronaphthalene  
   hydrochloride
   * dl-cis-2-Dimethylamino-1,2,3,4-tetrahydro-1-naphthol benzoate  
   hydrochloride
   * (+-)-cis-1,2,3,4-Tetrahydro-2-(dimethylamino)-1-naphthol benzoate  
   hydrochloride
   * (+-)-Yau 17
   * YAU-17 hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2200 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 26,842,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 164 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 26,842,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 14100 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 26,842,1976
 
                            *** END OF RECORD ***