*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QJ7000000
CHEMICAL NAME           : 2-Naphthaleneethylamine, beta-chloro-N-isopropyl-,
                          hydrochloride
CAS REGISTRY NUMBER     : 20794-96-1
LAST UPDATED            : 199304
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C15-H18-Cl-N.Cl-H
MOLECULAR WEIGHT        : 284.25
WISWESSER LINE NOTATION : L66J CYG1MY1&1 &GH
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 2-(alpha-Chloro-beta-isopropylamine)ethylnaphthalene hydrochloride
   * beta-Chloro-N-isopropyl-2-naphthaleneethylamine hydrochloride
   * ICI 42464
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 19800 mg/kg/38W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Blood - leukemia
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 10,183,1969
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 18 gm/kg/11W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Endocrine - tumors
REFERENCE :
   NATUAS Nature.  (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
   V.1-    1869-  Volume(issue)/page/year: 207,594,1965

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: Sperm morphology-mouse

 
                            *** END OF RECORD ***