*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QJ1897000
CHEMICAL NAME           : 2-Naphthalenecarboxamide,
                          3-hydroxy-4-((2-methoxy-5-nitrophenyl)azo)-N-(3-nitro
                          phenyl)-
CAS REGISTRY NUMBER     : 6471-49-4
LAST UPDATED            : 199701
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : C24-H17-N5-O7
MOLECULAR WEIGHT        : 487.46
WISWESSER LINE NOTATION : L66J BNUNR BO1 ENW& CQ DVMR CNW
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Alkali Resistant Red Dark
   * Calcotone Red 3B
   * Carnation Red Toner B
   * C.I. 12355
   * C.I. Pigment Red 157
   * Congo Red R-138
   * Fenalac Red FKB Extra
   * Malta Red X 2284
   * 2-Naphthanilide, 3-hydroxy-4-((2-methoxy-5-nitrophenyl)azo)-3'-nitro-
   * Naphthol Red B
   * Naphthol Red B 20-7575
   * Naphthol Red Deep 10459
   * Naphthol Red D Toner 35-6001
   * NCI-C60377
   * Pigment Red 23
   * Pigment Red BH
   * Rubescence Red MT-21
   * Sanyo Fast Red 10B
   * Sapona Red Lake RL-6280
   * Segnale Light Rubine RG
   * Textile Red WD-263
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 273 gm/kg/13W-C
TOXIC EFFECTS :
   Blood - normocytic anemia
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-411,1992
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 102 gm/kg/17D-C
TOXIC EFFECTS :
   Blood - pigmented or nucleated red blood cells
   Blood - changes in erythrocyte (RBC) count
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-411,1992
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 136 gm/kg/13W-C
TOXIC EFFECTS :
   Liver - changes in liver weight
   Endocrine - changes in thymus weight
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-411,1992
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 33 ug/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 8(Suppl
   7),1,1986
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 ug/plate
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-411,1992

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M2113
       No. of Facilities: 495 (estimated)
       No. of Industries: 16
       No. of Occupations: 34
       No. of Employees: 21254 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M2113
       No. of Facilities: 548 (estimated)
       No. of Industries: 11
       No. of Occupations: 24
       No. of Employees: 15233 (estimated)
       No. of Female Employees: 2716 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   NTP Carcinogenesis Studies (feed);equivocal:rat, no evidence:mouse
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-411,92

 
                            *** END OF RECORD ***