*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BO7000000
CHEMICAL NAME           : Ammonium, benzyldimethyloctadecyl-, chloride
CAS REGISTRY NUMBER     : 122-19-0
LAST UPDATED            : 199710
DATA ITEMS CITED        : 12
MOLECULAR FORMULA       : C27-H50-N.Cl
MOLECULAR WEIGHT        : 424.23
WISWESSER LINE NOTATION : 18K1&1&1R &G
COMPOUND DESCRIPTOR     : Drug
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Ammonyx 4
   * Ammonyx 485
   * Ammonyx 490
   * Ammonyx 4002
   * Ammonyx CA special
   * Arquad DM18B-90
   * 2B (onium compound)
   * Barquat SB-25
   * Benzenemethanaminium, N,N-dimethyl-N-octadecyl-, chloride
   * Benzyldimethylstearylammonium chloride
   * Benzylstearyldimethylammonium chloride
   * Carsoquat sdq-25
   * Carsoquat sdq-85
   * Dehyquart stc-25
   * Cation S (surfactant)
   * Dimethylbenzyloctadecylammonium chloride
   * Dimethyloctadecylbenzylammonium chloride
   * Intexan SB-85
   * Intexsan SB-85
   * J Soft C 4
   * Larostat HTS 905
   * Nissan cation S2-100
   * N-Octadecyl-N-benzyl-N,N-dimethylammonium chloride
   * Octadecyldimethylbenzylammonium chloride
   * Orthosan MB
   * Quaternol 1
   * Stearalkonium chloride
   * Stearyldimethylbenzylammonium chloride
   * Stebac
   * Stedbac
   * Tallow benzyl dimethyl ammonium chloride
   * Triton CG 400
   * Triton CG 500
   * Triton X-40
   * Triton X-400
   * Varisoft SDC
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Human
DOSE/DURATION           : 3 mg/3D (Intermittent)
REACTION SEVERITY       : Mild
REFERENCE :
   85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill,
   V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977
   Volume(issue)/page/year: -,127,1977
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 125 mg/2D
REACTION SEVERITY       : Mild
REFERENCE :
   PSTGAW Proceedings of the Scientific Section of the Toilet Goods
   Association. (Washington, DC) No.1-48, 1944-67.  Discontinued.
   Volume(issue)/page/year: 20,16,1953
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1 mg/24H
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 6,329,1972
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 200 ug
REACTION SEVERITY       : Severe
REFERENCE :
   PSTGAW Proceedings of the Scientific Section of the Toilet Goods
   Association. (Washington, DC) No.1-48, 1944-67.  Discontinued.
   Volume(issue)/page/year: 20,16,1953
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 1(2),57,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 760 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 1(2),57,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - somnolence (general depressed activity)
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 49(8),90,1984
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 364 mg/kg/26W-I
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Liver - liver function tests impaired
   Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 49(8),90,1984

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M5078
       No. of Facilities: 3432 (estimated)
       No. of Industries: 8
       No. of Occupations: 11
       No. of Employees: 35290 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M5078
       No. of Facilities: 2999 (estimated)
       No. of Industries: 3
       No. of Occupations: 5
       No. of Employees: 30960 (estimated)
       No. of Female Employees: 21084 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***