*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QI9446000
CHEMICAL NAME           : 5,12-Naphthacenedione,
                          7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(1-((4-hydrox
                          y-
                          1-methylbutylidene)hydrazono)ethyl)-1-methoxy-10-((2,
                          3-trideoxy-3-(((dimet hylamino)
                          methylene)amino)-alpha-L-lyxo-hexopyranosyl)oxy)-,
                          monohydrochloride, (8S-cis)-
CAS REGISTRY NUMBER     : 128948-06-1
LAST UPDATED            : 199206
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C35-H44-N4-O10.Cl-H
MOLECULAR WEIGHT        : 717.29
SYNONYMS/TRADE NAMES :
   * 3'-Desamino-3'-dimethylformamidinerubomycin  
   13-(5''-oxypentylidene-2'')hydrazone hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 64 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   ANKHEW Antibiotiki i Khimioterapiya.  Antibiotics and Chemotherapy. (V/O Me
   zhdunarodnaya Kniga, 113095 Moskow, USSR)  V.33-    1988-
   Volume(issue)/page/year: 35(4),21,1990
 
                            *** END OF RECORD ***