*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QI9335000
CHEMICAL NAME           : 5,12-Naphthacenedione,
                          7,8,9,10-tetrahydro-10-((3-amino-2,3,6-trideoxy-alpha
                          -L-lyxo
                          hexopyranosyl)oxy)-8-(1-hydroxyethyl)-1-methoxy-6,8,1
                          1-trihydroxy-
CAS REGISTRY NUMBER     : 28008-55-1
BEILSTEIN REFERENCE NO. : 3641654
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C27-H31-N-O10
MOLECULAR WEIGHT        : 529.59
WISWESSER LINE NOTATION : L E6 C666 BV MVT&&&J DQ HQ HYQ1 KQ RO1 FO- FT6OTJ B1
                          CQ DZ
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Antibiotic 20-798RP
   * Daunomycinol
   * Daunorubicinol
   * Dihydrodaunomycin
   * 13-Dihydrodaunomycin
   * 13-Dihydrodaunorubicin
   * Duborimycin
   * 1-Hydroxy-13-dihydrodaunomycin
   * Leukaemomycin D
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 3,122,1980
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 7600 nmol/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 34,1596,1981
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 3 umol/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 34,1596,1981
 
                            *** END OF RECORD ***