*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QI9325500
CHEMICAL NAME           : 5,12-Naphthacenedione,
                          7,8,9,10-tetrahydro-10-((3-amino-2,3,6-trideoxy-alpha
                          -L-lyxo-
                          hexopyranosyl)oxy)-8-(chloroacetyl)-1-methoxy-6,8,11-
                          trihydroxy-, (8S-cis)-
CAS REGISTRY NUMBER     : 121250-06-4
LAST UPDATED            : 199206
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C27-H28-Cl-N-O10
MOLECULAR WEIGHT        : 562.01
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 14-Chlorodaunorubicin
   * 14-Chlororubomycin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 33500 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   ANKHEW Antibiotiki i Khimioterapiya.  Antibiotics and Chemotherapy. (V/O Me
   zhdunarodnaya Kniga, 113095 Moskow, USSR)  V.33-    1988-
   Volume(issue)/page/year: 35(2),24,1990
 
                            *** END OF RECORD ***