*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QI9324250
CHEMICAL NAME           : 5,12-Naphthacenedione,
                          7,8,9,10-tetrahydro-10-((4-aminotetrahydro-5-iodo-6-m
                          ethyl-2H-pyran-2-
                          yl)oxy)-8-(hydroxyacetyl)-1-methoxy-6,8,11-trihydroxy
                          -, hydrochloride,
                          (2R-(2-alpha(8S*,10S*),4-beta,5-beta,6-beta))-
LAST UPDATED            : 199410
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C27-H28-I-N-O10.Cl-H
MOLECULAR WEIGHT        : 689.92
SYNONYMS/TRADE NAMES :
   * 4'-Deoxy-4'-iododoxorubicin hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3600 ug/kg/3W-I
TOXIC EFFECTS :
   Cardiac - EKG changes not diagnostic of specified effects
   Related to Chronic Data - death
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 70,243,1991
 
                            *** END OF RECORD ***