*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QI9297801
CHEMICAL NAME           : 5,12-Naphthacenedione,
                          7,8,9,10-tetrahydro-8-acetyl-10-((3-amino-2,3,6-tride
                          oxy-4-O-(3-
                          hydroxy-1-(2-hydroxy-1-methylethoxy)butyl)-alpha-L-ly
                          xo-hexopyranosyl)oxy) -1,6,8,11- tetrahydroxy-
CAS REGISTRY NUMBER     : 50935-06-3
LAST UPDATED            : 199509
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C33-H41-N-O13
MOLECULAR WEIGHT        : 659.75
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Carminomicin III
   * Carminomicin 3
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANTBAL Antibiotiki.  (Moscow, USSR)  V.1-29, 1956-84.  For publisher
   information, see AMBIEH.  Volume(issue)/page/year: 21(5),416,1976
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 400 ug/kg/10D-I
TOXIC EFFECTS :
   Blood - leukopenia
   Related to Chronic Data - death
REFERENCE :
   ANTBAL Antibiotiki.  (Moscow, USSR)  V.1-29, 1956-84.  For publisher
   information, see AMBIEH.  Volume(issue)/page/year: 21(5),416,1976
 
                            *** END OF RECORD ***