*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QI9279180
CHEMICAL NAME           : 1-Naphthacenecarboxylic acid,
                          2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,9-tetrahydroxy-6
                          ,11-
                          dioxo-4-((2,3,6-trideoxy-4-O-(2,6-dideoxy-4-O-((2R-tr
                          ans)-tetrahydro-6-met hyl-5-oxo-2H-
                          pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylam
                          ino)-alpha-L-lyxo-hex opyranosyl)oxy)-, methyl ester,
                          (1R-(1-alpha,2-beta,4-beta))-
CAS REGISTRY NUMBER     : 79127-36-9
BEILSTEIN REFERENCE NO. : 4901298
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C42-H53-N-O16
MOLECULAR WEIGHT        : 827.96
WISWESSER LINE NOTATION : L E6 C666 BV MVT&&&J FVO1 GQ G2 KQ OQ QQ IO- FT6OTJ
                          B1 DN1&1 CO- FT6OTJ B1 DQ CO- FT6O VTJ
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
                          Natural Product
SYNONYMS/TRADE NAMES :
   * 2-Hydroxyaclacinomycin A
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4474945
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 1030 nmol/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 34,1596,1981
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 170 nmol/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 34,1596,1981
 
                            *** END OF RECORD ***