*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QI7630100
CHEMICAL NAME           : 2-Naphthacenecarboxamide,
                          4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro
                          -3,10,12,12a- tetrahydroxy-1,11-dioxo-,
                          (4S-(4-alpha,4a-alpha,5a-alpha,12a-alpha))-,
                          disulfate (1:2) (salt)
LAST UPDATED            : 199706
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C23-H27-N3-O7.2H2-O4-S
MOLECULAR WEIGHT        : 653.69
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Minocycline disulfate
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 1714 mg/kg/30D-I
TOXIC EFFECTS :
   Blood - changes in erythrocyte (RBC) count
   Skin and Appendages - dermatitis, other (after systemic exposure)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   11,128,1967
 
                            *** END OF RECORD ***