*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD8525000
CHEMICAL NAME           : Morpholine,
                          4-((4,6-bis(1-methyl-4-piperidinyl)oxy)-5-(methylthio
                          )-2-pyrimidinyl)-
CAS REGISTRY NUMBER     : 57304-24-2
LAST UPDATED            : 199703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H35-N5-O3-S
MOLECULAR WEIGHT        : 437.67
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   4-((4,6-Bis(1-methyl-4-piperidinyl)oxy)-5-(methylthio)-2-pyrimidinyl)mor
     pholine
   * 2-Morpholino-4,6-di((4')-N-methylpiperidyl)-oxy-5-methylthiopyrimidin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 580 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2503136
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 53 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2503136
 
                            *** END OF RECORD ***