*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD2181000
CHEMICAL NAME           : Morphinan-6-one,
                          3,14-dihydroxy-4,5-alpha-epoxy-17-methyl-
CAS REGISTRY NUMBER     : 76-41-5
BEILSTEIN REFERENCE NO. : 0041588
REFERENCE               : 4-27-00-03681 (Beilstein Handbook Reference)
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H19-N-O4
MOLECULAR WEIGHT        : 301.37
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3,14-Dihydroxy-4,5-alpha-epoxy-17-methylmorphinan-6-one
   * 14-Hydroxydihydromorphinone
   * (14S)-14-Hydroxydihydromorphinone
   * Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-methyl-, (5-alpha)-
   * Oxymorphone
   * (-)-Oxymorphone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   3,261,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 172 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 84,280,1964
 
                            *** END OF RECORD ***