*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD2167000
CHEMICAL NAME           : Morphinan-6-one,
                          7,8-didehydro-4,5-alpha-epoxy-14-hydroxy-3-methoxy-17
                          -methyl-, propionate (ester)
CAS REGISTRY NUMBER     : 981-01-1
BEILSTEIN REFERENCE NO. : 4947278
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H23-N-O5
MOLECULAR WEIGHT        : 369.45
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Codeinone, 14-hydroxy-, propionate
   * Morphinan-6-one,  
   7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-14-(1-oxopropoxy)-,   (5-alpha)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 16(Suppl),68T,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 16(Suppl),68T,1964
 
                            *** END OF RECORD ***