*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD2164500
CHEMICAL NAME           : Morphinan-6-one,
                          7,8-didehydro-4,5-alpha-epoxy-14-hydroxy-3-methoxy-17
                          -methyl-, hexanoate (ester)
CAS REGISTRY NUMBER     : 1253-20-9
LAST UPDATED            : 199109
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C24-H29-N-O5
MOLECULAR WEIGHT        : 411.54
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Codeinone, 14-hydroxy-, hexanoate
   * Morphinan-6-one,  
   7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-14-((1-oxohexyl)oxy)-,  
   (5-alpha)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >459 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 16(Suppl),68T,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 16(Suppl),68T,1964
 
                            *** END OF RECORD ***