*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD2164250
CHEMICAL NAME           : Morphinan-6-one,
                          7,8-didehydro-4,5-alpha-epoxy-14-hydroxy-3-methoxy-17
                          -methyl-, cinnamate (ester), phosphate
LAST UPDATED            : 198508
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C27-H25-N-O5.H3-O4-P
MOLECULAR WEIGHT        : 541.53
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 14-Cinnamoyloxycodeinone phosphate
   * Codeinone, 14-hydroxy-, cinnamate, phosphate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 244 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 16(Suppl),68T,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 38 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 16(Suppl),68T,1964
 
                            *** END OF RECORD ***