*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD0874000
CHEMICAL NAME           : Morphinan-6-alpha-ol,
                          7,8-didehydro-4,5-alpha-epoxy-3-ethoxy-17-methyl-,
                          hydrochloride
CAS REGISTRY NUMBER     : 125-30-4
LAST UPDATED            : 199109
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C19-H23-N-O3.Cl-H
MOLECULAR WEIGHT        : 349.89
SYNONYMS/TRADE NAMES :
   * Codethyline hydrochloride
   * Dionine hydrochloride
   * Dionin hydrochloride
   * Ethylmorphine hydrochloride
   * O-Ethylmorphine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 21,727,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 771 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 15,640,1957
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 265 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 15,640,1957
 
                            *** END OF RECORD ***