*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QD0790000
CHEMICAL NAME           : Morphinan-6-alpha-ol,
                          7,8-didehydro-3-(2,4-dinitrophenoxy)-4,5-alpha-epoxy-
                          17-methyl-
CAS REGISTRY NUMBER     : 58534-70-6
BEILSTEIN REFERENCE NO. : 0071740
REFERENCE               : 4-27-00-02234 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H21-N3-O7
MOLECULAR WEIGHT        : 451.47
WISWESSER LINE NOTATION : T B6566 B6/CO 4ABBC R BX HO PN DU GHT&&TTJ FQ JOR BNW
                          DNW& P1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2,4-Dinitrophenyl ether of morphine
   * 2,4-Dinitrophenyl morphine
   * DNPM
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle weakness
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 67,127,1939
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Cardiac - EKG changes not diagnostic of specified effects
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 63,8,1938
 
                            *** END OF RECORD ***