*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QC9450000
CHEMICAL NAME           : Morphinan, 3-hydroxy-N-methyl-, hydrobromide, (-)-
CAS REGISTRY NUMBER     : 17140-05-5
LAST UPDATED            : 199012
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H23-N-O.Br-H
MOLECULAR WEIGHT        : 338.33
WISWESSER LINE NOTATION : T6 G666/FQ 2AF Q FX ONT&TTJ IQ O1 &EH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * l-Dromoran hydrobromide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Behavioral - stiffness
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 99,163,1950
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 46 mg/kg
TOXIC EFFECTS :
   Behavioral - stiffness
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 99,163,1950
 
                            *** END OF RECORD ***