*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QC7793000
CHEMICAL NAME           : Morphinan-3,14-diol, 17-(cyclobutylmethyl)-
CAS REGISTRY NUMBER     : 42408-82-2
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H29-N-O2
MOLECULAR WEIGHT        : 327.51
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * l-BC 2627
   * Butorphanol
   * (-)-Butorphanol
   * 17-(Cyclobutylmethyl)morphinan-3,14-diol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraspinal
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 35 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
   Behavioral - excitement
   Cardiac - pulse rate increase, without fall in BP
REFERENCE :
   AACRAT Anesthesia and Analgesia (New York).  (Elsevier Science Pub. Co.,
   Inc., 52 Vanderbilt Ave., New York, NY 10017)  V.36-    1957-
   Volume(issue)/page/year: 64,452,1985
 
                            *** END OF RECORD ***