*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QA4680000
CHEMICAL NAME           : Molybdenum
CAS REGISTRY NUMBER     : 7439-98-7
LAST UPDATED            : 199710
DATA ITEMS CITED        : 19
MOLECULAR FORMULA       : Mo
MOLECULAR WEIGHT        : 95.94
WISWESSER LINE NOTATION : MO
COMPOUND DESCRIPTOR     : Mutagen
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Molybdate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intratracheal
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 70 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis)
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB249-458
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 6050 ug/kg
SEX/DURATION            : female 35 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 42(8),30,1977
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5800 ug/kg
SEX/DURATION            : female 30 week(s) pre-mating
                          female 1-20 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 41,620,1978
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 448 mg/kg
SEX/DURATION            : multigenerations
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   AEHLAU Archives of Environmental Health.  (Heldref Pub., 4000 Albemarle St.,
   NW, Washington, DC 20016)  V.1-    1960-  Volume(issue)/page/year:
   23,102,1971
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Inhalation
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 19500 ug/m3
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 24(9),33,1980

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   JAVMA4 Journal of the American Veterinary Medical Association.  (American
   Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196)  V.48-
   1915-  Volume(issue)/page/year: 164,277,1974

   TOXICOLOGY REVIEW
   FOREAE Food Research.  (Champaign, IL)  V.1-25, 1936-60.  For publisher
   information, see JFDSAZ.  Volume(issue)/page/year: 7,313,1942

   TOXICOLOGY REVIEW
   KOTTAM Kogai to Taisaku.  Journal of Environmental Pollution Control. (Kogai
   Taisaku Gijutsu Dokokai, Shuwa-Akasaka Bldg., 9-1-244, Akasaka, Minato-ku,
   Tokyo 107, Japan)  V.1-    1965-  Volume(issue)/page/year: 11,1300,1975

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 48625
       No. of Facilities: 935 (estimated)
       No. of Industries: 17
       No. of Occupations: 29
       No. of Employees: 6097 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X5919
       No. of Facilities: 29 (estimated)
       No. of Industries: 2
       No. of Occupations: 6
       No. of Employees: 2426 (estimated)
       No. of Female Employees: 1114 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X5984
       No. of Facilities: 187 (estimated)
       No. of Industries: 5
       No. of Occupations: 11
       No. of Employees: 4474 (estimated)
       No. of Female Employees: 2432 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 48625
       No. of Facilities: 15780 (estimated)
       No. of Industries: 173
       No. of Occupations: 88
       No. of Employees: 238124 (estimated)
       No. of Female Employees: 4166 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   On EPA IRIS database
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NIOSH Analytical Method, 1994: Elements by ICP, 7300
   
   NIOSH Analytical Method, 1994: Metals in urine, 8310
   
   NIOSH Analytical Method, 1994: Elements in blood or tissue, 8005

 
                            *** END OF RECORD ***