*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PC4965000
CHEMICAL NAME           : Methanone,
                          (1-methyl-2-(1-methylethyl)-1H-indol-3-yl)-3-pyridiny
                          l-
CAS REGISTRY NUMBER     : 54270-10-9
BEILSTEIN REFERENCE NO. : 0662628
REFERENCE               : 5-24-04-00446 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H18-N2-O
MOLECULAR WEIGHT        : 278.38
WISWESSER LINE NOTATION : T56 BNJ B1 CY1&1 DV- CT6NJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * L 8180
   * (1-Methyl-2-(1-methylethyl)-1H-indol-3-yl)-3-pyridinylmethanone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 10,276,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 425 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 10,276,1975
 
                            *** END OF RECORD ***