*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PB9225000
CHEMICAL NAME           : 7,9a-Methano-9aH-cyclopenta(b)heptalene-4,8,11,11a,12
                          (1H)-pentol, 2,3-epoxydodecahydro-1,1,
                          4,8-tetramethyl-,
                          (2R,3S,3as,4R,4ar,7R,8R,9as,11R,11aR,12R)-
CAS REGISTRY NUMBER     : 26342-66-5
LAST UPDATED            : 199806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H32-O6
MOLECULAR WEIGHT        : 368.52
WISWESSER LINE NOTATION : T G3 E5 B765 A 1B Q BX HOTJ AQ DQ EQ F1 F1 KQ K1 PQ
                          P1
SYNONYMS/TRADE NAMES :
   * Grayanotoxane-5,6,10,14,16-pentol, 2,3-epoxy-,  
   (2-beta,3-beta,6-beta,14R)-
   * Rhodojaponin III
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   35,303,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 140 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   44,259,1980
 
                            *** END OF RECORD ***