*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PB9189000
CHEMICAL NAME           : 1H-2,8a-Methanocyclopenta(a)cyclopropa(e)cyclodecen-1
                          1-one, 2,5,5a,6,9,10,10a,1a-octahydro-
                          4-hydroxymethyl-1,1,7,9-tetramethyl-5,5a,6-trihydroxy
                          -, 5-hexadecanoate
CAS REGISTRY NUMBER     : 37394-33-5
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C36-H58-O6
MOLECULAR WEIGHT        : 586.94
COMPOUND DESCRIPTOR     : Tumorigen
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Ingenane hexadecanoate
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 82 ng
REACTION SEVERITY       : Mild
REFERENCE :
   85CVA2 "Oncology 1970, Proceedings of the Tenth International Cancer
   Congress," Chicago, Year Book Medical Pub., 1971  Volume(issue)/page/year:
   5,213,1970
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg/12W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   85CVA2 "Oncology 1970, Proceedings of the Tenth International Cancer
   Congress," Chicago, Year Book Medical Pub., 1971  Volume(issue)/page/year:
   5,213,1970
 
                            *** END OF RECORD ***