*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PB8805000
CHEMICAL NAME           : 2,6-Methano-3-benzazocin-8-ol,
                          1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-but
                          enyl)-, hydrochloride, (2-alpha,6-alpha,11R*)-(+-)-
CAS REGISTRY NUMBER     : 68964-90-9
LAST UPDATED            : 198703
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H27-N-O.Cl-H
MOLECULAR WEIGHT        : 321.93
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (+-)-Pentazocine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 151 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   PHMGBN Pharmacology: International Journal of Experimental and Clinical
   Pharmacology.  (S. Karger AG, Postfach CH-4009 Basel, Switzerland)  V.1-
   1968-  Volume(issue)/page/year: 12,39,1974
 
                            *** END OF RECORD ***