*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PB0822100
CHEMICAL NAME           : Methanesulfonanilide,
                          2'-hydroxy-5'-(1-hydroxy-2-(p-methoxyphenethylamino)p
                          ropyl)-, monohydrochloride
CAS REGISTRY NUMBER     : 7660-71-1
LAST UPDATED            : 199409
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H26-N2-O5-S.Cl-H
MOLECULAR WEIGHT        : 430.99
WISWESSER LINE NOTATION : WS1&MR BQ EYQY1&M2R DO1 &GH
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   *   2'-Hydroxy-5'-(1-hydroxy-2-(p-methoxyphenethylamino)propyl)methanesulfon
     anilide HCl
   * Mesuprine
   * Mesuprine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 22 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Musculoskeletal - tumors
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   22,279,1972
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 55 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   23,731,1972
 
                            *** END OF RECORD ***