*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : PB0822000
CHEMICAL NAME           : Methanesulfonanilide,
                          2'-hydroxy-5'-(1-hydroxy-2-(isopropylamino)ethyl)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 14816-67-2
LAST UPDATED            : 199309
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C12-H20-N2-O4-S.Cl-H
MOLECULAR WEIGHT        : 324.86
WISWESSER LINE NOTATION : WS1&MR BQ EYQ1MY1&1 &GH
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
SYNONYMS/TRADE NAMES :
   * 2'-Hydroxy-5'-(1-hydroxy-2-(isopropylamino)ethyl)-methanesulfonanilide  
   monohydrochloride
   * MJ 1992
   * Soterenol hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 13300 mg/kg/95W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Reproductive - Tumorigenic effects - ovarian tumors
   Tumorigenic - tumor types after systemic administration not seen
   spontaneously
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 12,13,1993
 
                            *** END OF RECORD ***