*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OS2158000
CHEMICAL NAME           : Melia toosendan Sieb. et Zucc., extract
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
COMPOUND DESCRIPTOR     : Drug
                          Human
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Chuanlianzi
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - child
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Cardiac - pulse rate increase, without fall in BP
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23,    1978-88. For
   publisher information, see ZYZAEU.  Volume(issue)/page/year: 21,211,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 221 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23,    1978-88. For
   publisher information, see ZYZAEU.  Volume(issue)/page/year: 21,211,1986
 
                            *** END OF RECORD ***