*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OQ2292460
CHEMICAL NAME           : Maytansine,
                          3-de(2-(acetylmethylamino)propionyloxy)-N-demethyl-3-
                          hydroxy-, 3-isovalerate
LAST UPDATED            : 198310
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C32-H43-Cl-N2-O9
MOLECULAR WEIGHT        : 635.22
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * C-15003 pnd-4
   * 3-De(2-(acetylmethylamino)propionyloxy)-N-demethyl-3-hydroxymaytansine  
   3-isovalerate
   * N-Demethylansamitocin P-4
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 2500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 35,82-54,1982
 
                            *** END OF RECORD ***