*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OO8050000
CHEMICAL NAME           : Mandelic acid, alpha-(2-thienyl)-,
                          1-methyl-3-piperidyl ester, hydrochloride
CAS REGISTRY NUMBER     : 36616-49-6
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H21-N-O3-S.Cl-H
MOLECULAR WEIGHT        : 367.92
WISWESSER LINE NOTATION : T5SJ BXQR&VO- CT6NTJ A1 &GH
SYNONYMS/TRADE NAMES :
   * JB 344
   * 1-Methyl-3-piperidyl-alpha-(2-thienyl)mandelate hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - ataxia
   Cardiac - pulse rate increase, without fall in BP
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 120,186,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 47 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - ataxia
   Cardiac - pulse rate increase, without fall in BP
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 120,186,1959
 
                            *** END OF RECORD ***