*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : OO7525000
CHEMICAL NAME : Mandelic acid, alpha-isopropyl-,
3-(dimethylamino)propyl ester, hydrochloride
CAS REGISTRY NUMBER : 60452-19-9
LAST UPDATED : 199012
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C16-H25-N-O3.Cl-H
MOLECULAR WEIGHT : 315.88
WISWESSER LINE NOTATION : 1Y1&XQR&VO3N1&1
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* BAY 1433
* Bayer 1433
* Bayer WH 4849
* 2-Hydroxy-3-methyl-2-phenylbutyric acid, 3-(dimethylamino)propyl ester
hydrochloride
* WH 4849
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 705 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,362,1972
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 336 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,362,1972
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 95 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,362,1972
*** END OF RECORD ***