*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : OO6950000
CHEMICAL NAME : Mandelic acid, alpha-cyclopentyl-,
1-ethyl-3-piperidyl ester, hydrochloride
CAS REGISTRY NUMBER : 467-68-5
LAST UPDATED : 199707
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C20-H29-N-O3.Cl-H
MOLECULAR WEIGHT : 367.96
WISWESSER LINE NOTATION : T6NTJ A2 COVXQR&- AL5TJ &GH
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 1-Ethyl-3-piperidyl-alpha-cyclopentyl mandelate
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3,
1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year:
2,17,1963
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 19 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness
Behavioral - ataxia
Cardiac - pulse rate increase, without fall in BP
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 120,186,1959
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 44 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness
Behavioral - ataxia
Cardiac - pulse rate increase, without fall in BP
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 120,186,1959
*** END OF RECORD ***