*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OM3850000
CHEMICAL NAME           : Magnesium oxide
CAS REGISTRY NUMBER     : 1309-48-4
LAST UPDATED            : 199712
DATA ITEMS CITED        : 33
MOLECULAR FORMULA       : Mg-O
MOLECULAR WEIGHT        : 40.31
WISWESSER LINE NOTATION :  MG  O
COMPOUND DESCRIPTOR     : Tumorigen
                          Human
SYNONYMS/TRADE NAMES :
   * Akro-mag
   * Animag
   * Calcined brucite
   * Calcined magnesia
   * Calcined magnesite
   * Granmag
   * Magcal
   * Magchem 100
   * Maglite
   * Magnesia
   * Magnesia USTA
   * Magnesium oxide fume
   * Magnezu tlenek
   * Magox
   * Magox 85
   * Magox 90
   * Magox 95
   * Magox 98
   * Magox OP
   * Marmag
   * Oxymag
   * Periclase
   * Seawater magnesia
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 400 mg/m3
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton,
   G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82.
   Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985.
   Volume(issue)/page/year: 2A,1745,1981
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1120 ug/m3/24H/29D-C
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - true cholinesterase
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 49(11),82,1984
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intratracheal
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 480 mg/kg/30W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Sense Organs and Special Senses (Olfaction) - tumors
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   33,2209,1973

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 10 mg/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 10 mg/m3 (fume)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,147,1971

   OSHA PEL (Gen Indu):8H TWA 15 mg/m3, total particulate
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 15 ppm, total particulate
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 15 ppm, total particulate
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 15 mg/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 10 mg/m3 JAN 1993
   
   OEL-AUSTRALIA:TWA 10 mg/m3 JAN 1993
   
   OEL-BELGIUM:TWA 10 mg/m3 JAN 1993
   
   OEL-DENMARK:TWA 6 mg/m3 JAN 1993
   
   OEL-FRANCE:TWA 10 mg/m3 JAN 1993
   
   OEL-GERMANY:TWA 6 mg/m3 JAN 1993
   
   OEL-HUNGARY:TWA 5 mg/m3;STEL 10 mg/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 10 mg/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 15 mg/m3 JAN 1993
   
   OEL-POLAND:TWA 15 mg/m3 JAN 1993
   
   OEL-RUSSIA:STEL 5 mg/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 6 mg/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 6 mg/m3;STEL 12 mg/m3 JAN 1993
   
   OEL-TURKEY:TWA 15 mg/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 10 mg/m3  (total dust) JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 80298
       No. of Facilities: 28931 (estimated)
       No. of Industries: 201
       No. of Occupations: 134
       No. of Employees: 354380 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 80298
       No. of Facilities: 42587 (estimated)
       No. of Industries: 258
       No. of Occupations: 177
       No. of Employees: 765812 (estimated)
       No. of Female Employees: 149523 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NIOSH Analytical Method, 1994: Elements by ICP, 7300
   
   OSHA ANALYTICAL METHOD #ID-125G

 
                            *** END OF RECORD ***