*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OL4025000
CHEMICAL NAME           : Lysergamide
CAS REGISTRY NUMBER     : 478-94-4
BEILSTEIN REFERENCE NO. : 0090708
REFERENCE               : 4-25-00-00937 (Beilstein Handbook Reference)
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H17-N3-O
MOLECULAR WEIGHT        : 267.36
WISWESSER LINE NOTATION : T C6656 1A P GN LM CUTT&&J EVZ G1
COMPOUND DESCRIPTOR     : Drug
                          Human
                          Natural Product
SYNONYMS/TRADE NAMES :
   * 9,10-Didehydro-6-methyl-ergoline-8-beta-carboxamide
   * Ergine
   * Ergoline-8-beta-carboxamide, 9,10-didehydro-6-methyl-
   * Lysergic acid amide
   * D-Lysergic acid amide
   * (+)-Lysergamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 14 ug/kg
TOXIC EFFECTS :
   Behavioral - toxic psychosis
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,97,1972
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 181,154,1936
 
                            *** END OF RECORD ***